Dehydrins (Dhns) are a group of intrinsically disordered land plant proteins that are closely associated with tolerance of dehydrative stress.Dhns are recognized and classified by the presence and sequence of five different conserved segments, varying in length from 8 to 15 residues, separated by highly variable disordered regions.In addition to on
Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement.To understand this process mechanistically, we investigated two Saccharomyces cerevisiae TFs, Reb1 and Cbf1.We sh
12" Speaker The article presents the concept of detecting subjects with balance disorders by the use of machine learning techniques.The proposed solution has been developed and tested based on a group of 40 subjects, the group included both patients with uncompensated dysfunction in the vestibular system and healthy volunteers.Presence of dysfuncti
JAK-STAT signaling pathway is an important cytokine signaling transduction pathway.Many monogenic loss-of-function or gain-of-function mutations in this pathway can cause inborn errors of immunity (IEI).Autoimmune diseases are caused by polygenic and different factors.The etiology of the disease is complex and diverse.The over-activation of JAK-STA